My 3-year old daughter is presently with measles. It started as high grade remittent fever for three days followed by maculopapular rash that started from the head downwards, very typical of the disease. This occurrence frustrated us, especially my wife who's a pediatrician, because my daughter received 2 doses of measles vaccine already, following strictly the recommended scheduled. It made us think and somewhat doubt the effectivity of the vaccines. But, as doctors, we knew this could happen. We are familiar with 'vaccine failures' and we just felt sorry that our daughter is now included in the small unfortunate population of victims. The rate of vaccine failure is reported to be around 9.5% for measles virus. Most cases of measles in vaccinated persons occur in the subset of individuals who did not undergo serological conversion after vaccination. This is known as primary vaccine failure. The frequency of primary vaccine failure is variable and has been shown to be a f...